Bone Marrow Niche: Key Factors for Plasma Cells Longevity
The research revealed that the combined stimulus of the MSC secretome and hypoxia induces a profound metabolic switch within the plasma cell. Recent breakthrough in Immunology has shown that there are some specific microenvironmental factors within the bone marrow (BM) that are required for sustaining the viability and functions of Human Long-Lived Plasma Cells (LLPCs), indispensable for long-term humoral immunity. While initial Antibody-Secreting Cells, found in the blood ar
Anjali Singh
3 days ago2 min read
The Immortal Jellyfish: Nature’s Secret to Never Growing Old
When faced with starvation, injury, or old age it performs an extraordinary trick; it reverses its life cycle. In the calm blue waters of the Mediterranean there exists a creature with an extraordinary ability. The Turritopsis dohrnii carries a title no other creature can claim: the immortal jellyfish. Most animals live, age and die but this jellyfish doesn’t always follow that script. When faced with starvation, injury, or old age it performs an extraordinary trick; it reve
Anika Thakur
Nov 33 min read
Engineered Bacteria as Trojan Horses in Cancer Therapy
It is indeed revolutionary how something as simple as a bacterium can be engineered to tackle such illness. In an innovative leap for cancer treatment, researchers have engineered bacteria to act as “Trojan horses” carrying cancer-killing viruses directly into tumours. This strategy overcomes a long-time barrier in oncolytic virotherapy by delivering viruses past the body’s defences deep into solid tumours. The new work, published in Nature Biomedical Engineering, describes a
Aanya Uniyal
Oct 162 min read
Sniffing Out Disease: Meet the HeroRATs
In a world where fast diagnostics are critical, big solutions can come from the unlikeliest of places.
Aaisha Shoeb
Sep 232 min read
